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THE HORIZON
SECTION 20
ISSUE 001
PROJECTIONhypothesis1-3yconfidence / low
Models Choose Better Model Organisms
Hypothesis: cross-species foundation models can select the organism that provides the most informative experiment for a human biological question. Compare model-selected organisms with expert choice across prospective studies, scoring translational validity, cost, time, and surprise, while preventing benchmark leakage from well-studied species.
Why this idea is here
What the evidence establishes.
Cross-domain genomic and unified biological models provide representations spanning organisms and molecular modalities, enabling prospective organism-selection experiments.
Source ledger
Read the sources.
- S01Genome Modelling and Design Across All Domains of Life with Evo 2
peer-reviewed primary research / dated 2026 / retrieved 2026-07-09
- S02Generalized Biological Foundation Model with Unified Nucleic Acid and Protein Language
peer-reviewed primary research / published 2025-06-18 / retrieved 2026-07-09